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Case Report

Impact of Endosulfan on Male Reproductive functions - a review

Year : 2016 | Volume : 4 | Issue : 2 Page : 44 - 49

Srinivasa Jayachandra



Address for correspondence: Dr. Srinivasa Jayachandra, Associate Professor, Department of Physiology,Fathima Institute of Medical Sciences,Kadapa,Andhra Pradesh, India.

Email: jayachandra.srinivasa@gmail.com

Abstract

Introduction: Endosulfan is an organochlorine insecticide and acaracide used to control a broad range of insect and arthropod pests on a wide variety of crops in many agrosystems. It can cause acute and chronic toxicity. Endosulfan is a neurotoxin, haematoxin, genotoxin and nephrotoxin. Toxicity of this insecticide on reproductive organs is confirmed. So this article reviews experimental and epidemiological studies of reproductive toxicity of endosulfan in males. The Literature search was carried on PubMed for the years 1994 -2014. Twelve experimental studies and two human studies on Male Reproductive Toxicity induced by endosulfan were identified. Based on the findings, it suggest that endosulfan can affect the male reproductive system and also that these effects are likely to be larger if exposure occurs during the developmental phase. Further investigation of endosulfan as reproductive toxicant is warranted.

Keywords :Endosulfan, Organochlorine insecticide, Male reproductive system.

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